LOCUS       ISCR1-ampC unit                    5180 bp    DNA     linear       26-OCT-2020
DEFINITION  Proteus vulgaris.
ACCESSION
VERSION
KEYWORDS    .
SOURCE      Proteus vulgaris
  ORGANISM  Proteus vulgaris
            Unclassified.
REFERENCE   1  (bases 1 to 5180)
  AUTHORS   Zhou,D.
  TITLE     The complete sequence of ISCR1-ampC unit
  JOURNAL   Unpublished
REFERENCE   2  (bases 1 to 5180)
  AUTHORS   Zhou,D.
  TITLE     Direct Submission
  JOURNAL   Submitted (26-OCT-2020) State Key Laboratory of Pathogen and
            Biosecurity, Beijing Institute of Microbiology and Epidemiology,
            Beijing, Beijing 100071, China
FEATURES             Location/Qualifiers
     source          1..5180
                     /organism="Proteus vulgaris"
                     /mol_type="genomic DNA"
     mobile_element  1..5180
                     /gene="ISCR1-ampC unit"
                     /product="Putative resistance unit: ISCR1-ampC unit"
     mobile_element  complement(1..2154)
                     /gene="ISCR1"
                     /product="Insertion sequence: ISCR1"
     CDS             381..1922
                     /gene="tnpA"
                     /codon_start=1
                     /transl_table=11
                     /product="ISCR1 transposase"
                     /translation="MSLARNATASQSPTQTNGYERHQPDQTLLYQLVEQHYPAFKASL
                     EAQGQHLPRYIQQEFNDLLQCGRLEYGFMRVRCEDCHHERLVAFSCKRRGFCPSCGAR
                     RMAESAALLIDEVFPKEPIRQWVLSFPFQLRFLLARHPQLMGQVLSIVYRTLSTHLIK
                     KAGYTKASAQTGSVTLIQRFGSALNLNVHYHMLFLDGVYAEDDYGKQRFHRVKAPTYD
                     ELNTLAHTLSHRIARCMEKRGILERDAENTWLTLEEGEDDTLTQLHGASVTYRIAVGP
                     QQGRKVFTLQTLPGREDKADSSSRVANHAGFSLHAGVMAEAHQRDKLERLCRYISRPA
                     VSEKRLALTANGQVRYELKTPYRNGTTHVIFEPLDFIAKLAALVPKPRVNLTRFHGVF
                     APNSKHRVQVTPAKRGKKPDKSEGLDTNWRDKSPAERHRAMTWMQRLKRVFNIDIEVC
                     EHCGGHVKVIASIEDPKVIEQILKHLKQKTAKANAAKQRELPPERAPPLTPSLFDPSQ
                     SRLFD"
     CDS             complement(2100..2540)
                     /codon_start=1
                     /transl_table=11
                     /product="Putative exported protein"
                     /translation="MDVLRFILRLPFILLRLAARSLVYLFTLLGFLLRPFTGRIRWAV
                     PGWVTFAGNQLARLERGGNRYPKTISALLLLTAAVAAGSYYTWHWYQNKPKPVDVAPL
                     VVQDISASVQRPSAVNYNRDDNSAQIVGIGSINHLFAPHPKYLT"
     repeat_region   2134..2154
                     /gene="oriIS"
                     /product="ISCR1 oriIS"
     CDS             complement(2735..3874)
                     /gene="ampC"
                     /codon_start=1
                     /transl_table=11
                     /product="Class C beta-lactamase DHA-1"
                     /translation="MKKSLSATLISALLAFSAPGFSAADNVAAVVDSTIKPLMAQQDI
                     PGMAVAVSVKGKPYYFNYGFADIQAKQPVTENTLFELGSVSKTFTGVLGAVSVAKKEM
                     ALNDPAAKYQPELALPQWKGITLLDLATYTAGGLPLQVPDAVKSRADLLNFYQQWQPS
                     RKPGDMRLYANSSIGLFGALTANAAGMPYEQLLTARILAPLGLSHTFITVPESAQSQY
                     AYGYKNKKPVRVSPGQLDAESYGVKSASKDMLRWAEMNMEPSRAGNADLEMAMYLAQT
                     RYYKTAAINQGLGWEMYDWPQQKDMIINGVTNEVALQPHPVTDNQVQPYNRASWVHKT
                     GATTGFGAYVAFIPEKQVAIVILANKNYPNTERVKAAQAILSALE"
     CDS             3985..4860
                     /gene="ampR"
                     /codon_start=1
                     /transl_table=11
                     /product="LysR-type transcriptional regulator"
                     /translation="MVRRYLPLNPLRAFEAAARHLSFTRAAIELNVTHAAVSQQVRAL
                     EEQLGCVLFTRVSRGLVLTHEGEGLLPVLNEAFDRIADTLECFSHGQFRERVKVGAVG
                     TFAAGWLLPRLAGFYDSHPHIDLHISTHNNHVDPAAEGHDYTIRFGNGAWHESDAELI
                     FSAPHAPLCSPAIAEQLQQPDDVHRFTLLRSFRRDEWSRWLDCAGGTPPSPSQPVMVF
                     DTSLAMAEAAQLGAGVAIAPVCMFSRLLQSGALVQPFAAEITLGGYWLTRLQSRTETP
                     AMQQFARWLLNTAAA"
BASE COUNT     1236 a   1484 c   1328 g   1132 t
ORIGIN
        1 aatatctcct tttgggttgt taataaaaca tccaataagt tgactgtgcg tgaaaaagaa
       61 agttttgtgt gatggcgttg aagatcgcac cgttaagctc ttatgtggga tggtgcagag
      121 ctcgacgact accgataaaa cgcaaccgcc gcaaacagac aagaaaaagc cccaactgat
      181 aacagttggg gcttcagtat tgtgattggt ggagcaatag caccctgaac ccaaaacctt
      241 ctcgctcaac cggtagtggc tgataacaac tcgtgagggc tattgcgggt taagcattta
      301 gcgatgtcta gggccagact ggacgtctga acgcaagccg ctgatactgt acataaccac
      361 agtatcagcg gaggataccc atgtcgctgg caaggaacgc cacggcgagt caatcgccca
      421 ctcaaacaaa cggttacgaa cgccaccaac ccgaccagac gctgctctac cagctggttg
      481 agcagcacta cccagccttc aaagcctcac tcgaagccca aggtcaacac ctgcctcgct
      541 acatccaaca agaattcaac gacctcctcc aatgtggccg tctggagtat ggtttcatgc
      601 gggttcgctg cgaggattgt catcacgagc gtctggtcgc cttcagctgt aaacgacgcg
      661 gcttttgccc tagctgcggt gcccgccgga tggccgagag tgcggcgctg ctgatagacg
      721 aagtcttccc caaggagccc attcgccagt gggtgctcag ctttcctttc cagctacgct
      781 ttttgctggc tcgccatccc cagctgatgg gccaggtctt gagtatcgtc tatcgtacac
      841 tctcaactca tctgatcaaa aaagccggtt acaccaaagc ctctgcacaa actggctcag
      901 tgactcttat ccaacgcttt ggctccgcgc taaatctcaa tgtccactac cacatgctgt
      961 ttctcgatgg tgtctatgcc gaagatgact atggcaagca acgcttccat cgtgtcaagg
     1021 cacccactta cgatgagctg aatacgctcg ctcacaccct cagccatcgc atcgctcgct
     1081 gcatggaaaa gcgtgggatt ttggagcgtg atgccgagaa tacgtggttg acactggaag
     1141 agggcgaaga cgatacgctg actcaattac atggtgcttc ggttacgtat cgcattgccg
     1201 tcggccccca gcaagggcgc aaagtcttca ccctgcaaac cttgccaggg cgtgaggata
     1261 aagccgactc aagcagtcga gtagccaacc atgctggttt ctcgctacac gccggtgtga
     1321 tggccgaagc gcatcagcgg gataagcttg agcgcttgtg tcgctacatt agtcggccag
     1381 cggtttcaga aaaacgtctg gcattaaccg ccaatgggca ggtgcgttac gagctcaaaa
     1441 ctccgtaccg caatggcacc acccatgtga tcttcgagcc gctggacttc atcgccaaac
     1501 tcgctgcgtt ggtacctaag ccgcgagtca acctcacacg cttccacggc gtctttgcac
     1561 cgaacagcaa acaccgagtt caagtaacac ccgccaagcg gggcaagaag cccgacaaat
     1621 cggaaggtct cgatactaac tggcgtgaca agagtcctgc agagcgccac cgcgccatga
     1681 cctggatgca acgcctcaag cgagtcttca atattgatat tgaagtctgc gaacactgcg
     1741 gcggtcacgt caaagtgatt gccagcatcg aagatccgaa ggtcattgag cagattctca
     1801 agcatctgaa acagaaaaca gccaaggcga atgccgccaa gcagcgtgag ctgccaccag
     1861 aacgagcgcc gccactgact cccagcctgt tcgatccatc acagagtcgt ctctttgact
     1921 gacgacccca aatccaacac tgctcaacac tgccaacttt taaacggggc ggtggggcag
     1981 tttgtatctc tcgagctatc aggctagaga ttttaccgcc aaatcgaacc ttattagagc
     2041 ggtttaggct ggaccggcag ttaaaattgg ggcttgagcg gtaaacgagt gagggaattt
     2101 caggtaagat acttcggatg aggagcaaaa aggtggttta tacttcctat acccacaatc
     2161 tgcgctgaat tatcatcacg gttataatta accgccgaag ggcgctgcac agacgcggaa
     2221 atatcctgca ccaccagcgg cgcaacatcc accggcttcg gtttgttctg ataccagtgc
     2281 caggtgtaat aactgcccgc tgccaccgca gcagtcagta ataataaggc agatatggtt
     2341 ttcggatagc ggttgccccc ccgctccagc cgggcaagct gattaccggc aaaggtcacc
     2401 cagcccggca ccgcccagcg gatccgtccg gtgaacgggc gcagcagaaa acccagcaga
     2461 gtaaagagat aaacaagact gcgagccgcc agacgcagca aaataaaagg taagcggagg
     2521 ataaaacgca gaacgtccat gacaacattt tcctctgtgt gttgagactg acatcagttt
     2581 gccgcagcac acagtgaaat ccggttcagc cggaagctgt cagtgcccga tactctcatc
     2641 ctccataaaa cagcccataa agcaaattat tgcataagga ataatcttaa attacggccc
     2701 cggcgtatcc gcaggggcct gttcaggaaa aaaattattc cagtgcactc aaaatagcct
     2761 gtgcagcttt gactctttcg gtattcgggt agtttttatt cgccagaatc acaatcgcca
     2821 cctgtttttc cggaataaag gcgacatagg cgccgaaacc agttgttgcg cccgttttat
     2881 gcacccagga agcacggtta tacggctgaa cctggttgtc tgttaccgga tgcggctgca
     2941 atgcgacctc gttggtcaca ccgttaatga tcatatcttt ctgctgcggc cagtcataca
     3001 tttcccagcc cagcccctgg ttaatcgcgg cggttttata gtagcgggtc tgggcgagat
     3061 acattgccat ttccagatcc gcattaccgg cccgtgacgg ctccatattc atttccgccc
     3121 agcgcagcat atcttttgag gcggatttca cgccgtaaga ttccgcatca agctgtcccg
     3181 gcgacacgcg gaccggtttt ttgtttttat aaccgtacgc atactggctt tgcgcacttt
     3241 ccggcacagt aataaaggtg tgagataacc ccagcggtgc caggatccgt gcagtcagca
     3301 actgctcata cggcatcccc gccgcgtttg cggtcagagc accaaacagg ccgatactgc
     3361 tgtttgcata cagacgcata tcgcccggtt tccgggacgg ctgccactgc tgatagaaat
     3421 tcagcagatc cgcacggctt tttaccgcat ccggcacctg taacggcagt ccgcctgcgg
     3481 tataggtagc cagatccagc aatgtgatcc ccttccactg cggcagagcc agctccggct
     3541 ggtattttgc cgccggatca ttcagcgcca tctctttttt cgccacagaa accgcaccca
     3601 gcacacctgt gaaagtttta cttacagatc cgagctcaaa tagtgtattt tcagtgaccg
     3661 gctgttttgc ctgaatatcg gcaaaaccat aattgaaata atagggctta ccctttacgg
     3721 agacggcaac cgccatcccg ggaatatcct gctgtgccat cagcggttta atggtgctgt
     3781 ccaccaccgc cgcgacatta tcagcggcag aaaaccccgg ggcggaaaac gccagcagag
     3841 cggaaatcag tgttgcagat aacgattttt tcatcagaat taaccttccg tgtgtgagta
     3901 acggcggcaa gtatagtcag attcaccgga cagaacaaac ggttatttat aacaagagcc
     3961 taaagaaaaa cttacaggtg gattatggtc agacgttatc tcccccttaa cccgctgcgc
     4021 gcctttgagg ccgccgcccg tcatctcagt tttacccgcg cggcgattga gctgaatgtc
     4081 acccatgccg ccgtcagcca gcaggtcagg gcgctggaag aacaactcgg ctgtgtgctg
     4141 tttacccgcg tctcgcgcgg gctggtgctg acccatgaag gtgagggatt actgccggtg
     4201 ctcaatgagg cgtttgaccg gattgcggat actctggagt gtttttctca cgggcagttc
     4261 cgtgagcggg tgaaagtcgg tgcggtggga acatttgccg caggctggct gctgccgcgt
     4321 ctggccggat tctatgacag ccatccgcat attgatctgc atatctccac ccataacaat
     4381 catgtggacc cggcggcgga agggcatgat tatacgatcc gtttcggtaa cggcgcgtgg
     4441 catgagtcag atgcggaact gattttcagt gcaccacacg ctccgctgtg ctcaccggcc
     4501 attgcagaac agttacagca gccggatgat gttcaccgct ttaccctgct gcgctcattc
     4561 cgccgggatg aatggagccg ctggctggat tgtgcgggcg gcacaccgcc ttccccgtca
     4621 cagccggtaa tggtgttcga tacctcactg gccatggccg aggcggcaca actgggtgcc
     4681 ggggtagcga tcgcaccggt atgtatgttc agccgcctgt tacagtcagg cgcactggta
     4741 cagccgtttg ccgcagaaat caccctcggc ggctactggc tgacgcggtt acagtcccgt
     4801 acggaaaccc cggccatgca gcaattcgcc cgctggctgc tgaatacggc ggcggcgtaa
     4861 aactcactca ccttccaggc tttttacccg caaatcatca ccttcactga tgcgcagccg
     4921 ttcactgccg cagtgcggac agcatccggc gtgctgcatg atttcggcct cacggctgca
     4981 atcccagcac catgcctgtg ccgggataac atcaatatgc agtgtgcagc cctgcgccac
     5041 ggtatcacgg caggcgatat caaaacagaa atgcagtgca ctctcctcaa catccgccag
     5101 tgcgccgact tccagccaga catccgttac ccgcgcaatg ccgtgctgtt cagcctgttc
     5161 gcggataatg tccgccgcac
//
